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1,2-Bis(2-iodoethoxy)ethane
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:36839-55-1
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

1,2-Bis(2-iodoethoxy)ethane is a PEG-based PROTAC linker. 1,2-Bis(2-iodoethoxy)ethane can be used in the synthesis of MT802 (HY-122562) and SJF620 (HY-133137). MT-802 and SJF620 are highly potent PROTAC BTK degraders with DC50s of 1 nM and 7.9 nM, respectively. References: [1]. Jaime-Figueroa S, et al. Design, synthesis and biological evaluation of Proteolysis Targeting Chimeras (PROTACs) as a BTK degraders with improved pharmacokinetic properties. 2020 Feb 1;30(3):126877.

纯度:≥98%

CAS:36839-55-1