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Isorhamnetin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Isorhamnetin图片
CAS NO:480-19-3
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
3'-Methylquercetin
3-methylquercetin
异鼠李素
3'-Methoxyquercetin
Isorhamnetol
产品介绍
Isorhamnetin 是从中草药沙棘中提取的一种类黄酮,可通过抑制MEK1和PI3K来抑制皮肤癌。

产品描述

Isorhamnetin is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injuries from oxidized LDL via inhibition of lectin-like ox-LDL receptor-1 upregulation, interference of ox-LDL-mediated intracellular signaling pathway (p38MAPK activation, NF-kappaB nuclear translocation, eNOS expression) and the antioxidant activity of isorhamnetin. Isorhamnetin prevents endothelial dysfunction, superoxide production, and overexpression of p47phox induced by angiotensin II. Isorhamnetin appears to be a potent drug against esophageal cancer due to it's in vitro potential to not only inhibit proliferation but also induce apoptosis of Eca-109 cells.

Cas No.

480-19-3

分子式

C16H12O7

分子量

316.265

别名

3'-Methylquercetin;3-methylquercetin;异鼠李素;3'-Methoxyquercetin;Isorhamnetol

储存和溶解度

DMSO:28 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years