Ajmaline 是一种钠通道阻断剂，属于1A 类抗心律失常剂。Ajmaline 阻断 HERG 电流，在 HEK 细胞的 IC50为 1 μM，爪蟾卵母细胞的IC50为 42.3 μM。Ajmaline 在室性心动过速方面具有研究价值。

Ajmaline is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or ventricular tachycardia. Ajmaline inhibits cardiac Kv1.5 and Kv4.3 channels at therapeutic concentrations.

4360-12-7

C20H26N2O2

326.44

阿义马林;(+)-Ajmaline;Cardiorythmine;阿义吗啉;Tachmalin;Raugalline

DMSO:59 mg/mL(180.8 mM)
Chloroform:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years