NortrAChElogenin is a novel agent for proSTATe cancer tHERapy with ability to inhibit Akt membrane localization and activity as well as the activation of growth factor receptors, tHEReby efficiently synergizing with tumor necROSis factor-related Apoptosis-inducing ligand (TRAIL), exposure.NortrAChElogenin has anti-inflammatory properties,it shows moderate inhibiting activities on NF- ?oB signaling pathway induced by TNF-α , with the IC50 value of 49.4 uM. NortrAChElogenin also shows anti-plaSmodium activity of 14.50 dg/ml. (+ )-NortrAChElogenin shows effects on the central nervous system producing depression in rabbits, it is moderately active against HIV-1 in vitro. (-)-NortrAChElogenin exerts its Antibacterial effect by disorganizing and perturbing the cytoplasmic membrane, it also can induce membrane disruption and Caspase-dependent Apoptosis.

Nortrachelogenin is a novel agent for prostate cancer therapy with ability to inhibit Akt membrane localization and activity as well as the activation of growth factor receptors, thereby efficiently synergizing with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), exposure.Nortrachelogenin has anti-inflammatory properties,it shows moderate inhibiting activities on NF- IoB signaling pathway induced by TNF-α , with the IC50 value of 49.4 uM. Nortrachelogenin also shows anti-plasmodium activity of 14.50 dg/ml. (+ )-Nortrachelogenin shows effects on the central nervous system producing depression in rabbits, it is moderately active against HIV-1 in vitro. (-)-Nortrachelogenin exerts its antibacterial effect by disorganizing and perturbing the cytoplasmic membrane, it also can induce membrane disruption and caspase-dependent apoptosis.

34444-37-6

C20H22O7

374.38

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years