Byakangelicol 是一种分离自白芷的白三醇，能够抑制环加氧酶-2的表达及活性，从而减少白细胞介素-1β诱导的 A549 细胞中前列腺素 E2 的释放。它可用于研究气道炎症。

1. Byakangelicol may inhibit P-gp expressed at the BBB even under in vivo conditions. 2. Byakangelicol can inhibit IL-1beta-induced PGE2 release in A549 cells; this inhibition may be mediated by suppression of COX-2 expression and the activity of COX-2 enzyme, thus it may have therapeutic potential as an anti-inflammatory drug on airway inflammation.

26091-79-2

C17H16O6

316.309

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble
DMSO:55 mg/ml (173.89 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years