Icaritin 是EPimedium Genusis的异戊二烯类黄酮衍生物，有效抑制 K562 细胞和原代 CML 细胞的增殖。它可以调节MAPK/ERK/JNK和JAK2/STAT3/Akt信号传导，并具有增强成骨的作用。

Icaritin has hormone regulation activity and cardiovascular function improvement activity. Icaritin has anticancer activity, can induce S phase arrest and apoptosis, inhibit ENKL cell proliferation. Icaritin has anti-multiple myeloma activity, mainly mediated by inhibiting IL-6/JAK2/STAT3 signaling. Icaritin at low concentration (4 or 8 μMol/L) can promote rat chondrocyte proliferation and inhibit cell apoptosis, while the effect of Icaritin on rat chondrocyte at high concentration was reversed.

118525-40-9

C21H20O6

368.385

去水淫羊藿黄素;Anhydroicaritin;Cycloicaritin

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble
DMSO:16 mg/mL(43.4 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years