Tetrahydroxystilbene-2-O-β-D-glucoside 是一种低分子量的促红细胞生成素诱导剂。

Tetrahydroxystilbene-2-O-β-D-glucoside is a low MW inducer of erythropoietin. Tetrahydroxystilbene-2-O-β-D-glucoside induces expression of erythropoietin, PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astrocytes and PC12 neuronal-like cells. In vivo, Tetrahydroxystilbene-2-O-β-D-glucoside treatment restores memory impairment, as assessed by the passive avoidance test, in SD, Aβ and KA mouse models. In the hippocampus of mice given Tetrahydroxystilbene-2-O-β-D-glucoside in their diet, levels of erythropoietin, PGC-1α and haemoglobin were increased. Treatment with Tetrahydroxystilbene-2-O-β-D-glucoside might be a therapeutic strategy for memory impairment in neurodegenerative disease, physiological ageing or traumatic brain injury.

55327-45-2

C20H22O9

406.38

EH-201;tetrahydroxyl diphenylethylene-2-o-gluco;何首乌苷

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years