Triptonide 是从雷公藤中鉴定出的一种天然产物，是一种Wnt信号抑制剂，其IC50约为 0.3 nM。它具有免疫抑制、抗炎、避育、神经保护和抗淋巴瘤作用。

1. Triptonide is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-inflammatory activity, upregulate the expression of IL-37, and this expression was suppressed by ERK1/2 and p38 MAPK inhibitors.

38647-11-9

C20H22O6

358.39

雷公藤内酯酮;PG 492;NSC 165677

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years