Malvidin-3-O-glucoside chloride 是一种主要的葡萄酒花青素，能够调节大脑突触可塑性和外周炎症，促进应激反应的发生。

Malvidin-3-O-glucoside chloride has antioxidant activity, alone is not oxidized in the presence of grape polyphenol oxidase. Malvidin-3-O-glucoside chloride's color stabilization at a higher pH can be explained by self-aggregation of the flavylium cation and copigmentation with the Z-chalcone form.

Here we used a gel electrophoresis assay employing supercoiled DNA plasmid to examine the ability of these compounds (1) to intercalate DNA, (2) to inhibit human topoisomerase I through both inhibition of plasmid relaxation activity (catalytic inhibition) and stabilization of the cleavable DNA-topoisomerase complex (poisoning), and (3) to inhibit or enhance oxidative single-strand DNA nicking. We found no evidence of DNA intercalation by anthocyan(id)ins in the physiological pH range for any of the compounds used in this study-cyanidin chloride, cyanidin 3-O-glucoside, cyanidin 3,5-O-diglucoside, Malvidin-3-O-glucoside chloride and luteolinidin chloride. The anthocyanins inhibited topoisomerase relaxation activity only at high concentrations (>50 muM) and we could find no evidence of topoisomerase I cleavable complex stabilization by these compounds.

7228-78-6

C23H25ClO12

528.89

氯化锦葵色素-3-Β-葡糖苷;Oenin chloride;Malvidin-3-O-glucoside chloride

DMSO:20 mg/ml (28.36 mM)
DMF:20 mg/ml (28.36 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years