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γ-Fagarine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
γ-Fagarine图片
CAS NO:524-15-2
包装:1 mg
市场价:-1元

产品名称
γ-崖椒碱
gamma-Fagarine
产品介绍

产品描述

gamma-Fagarine possesses moderate levels of anti-HCV activities with IC50 values being 20.4 ± 0.4 ug/ml, respectively. It has sister chromatid exchanges (SCEs)-inducing activity

体外活性

In this study, we examined extracts, their subfractions and isolated compounds of Ruta angustifolia leaves for antiviral activities against HCV in cell culture. We isolated six compounds, chalepin, scopoletin, γ-fagarine, arborinine, kokusaginine and pseudane IX. Among them, chalepin and pseudane IX showed strong anti-HCV activities with 50% inhibitory concentration (IC50) of 1.7 ± 0.5 and 1.4 ± 0.2 μg/ml, respectively, without apparent cytotoxicity. Their anti-HCV activities were stronger than that of ribavirin (2.8 ± 0.4 μg/ml), which has been widely used for the treatment of HCV infection[1]

Cas No.

524-15-2

分子式

C13H11NO3

分子量

229.23

别名

γ-崖椒碱;gamma-Fagarine

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years