Gnetol 是从买麻藤的根中分离出来的一种酚类。它是酪氨酸酶抑制剂,对鼠酪氨酸酶的IC50为 4.5 μM,可抑制黑色素的生物合成。它有效抑制COX-1和HDAC,具有抗氧化、抗增殖、抗癌和保肝活性,还具有浓度依赖性的 α-淀粉酶、α-葡萄糖苷酶和脂肪形成活性。
产品描述
Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells. It is active in the inhibition of arachidonic acid (AA)-induced platelet aggregation.
Cas No.
86361-55-9
分子式
C14H12O4
分子量
244.246
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years