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Neosmitilbin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Neosmitilbin图片
CAS NO:54081-47-9
包装:5 mg
市场价:1300元

产品名称
新落新妇苷
Neoastilbin
产品介绍
Neosmitilbin 分离于Garcinia?mangostana。它能够有效抑制晶状体醛糖还原酶的活性,可能具有抗氧化和抗炎作用。

产品描述

Neoastilbin may have antioxidant and anti-inflammatory activities, it shows potent inhibition of lens aldose reductase.

体外活性

Phenolic-enriched extract of S. glabra (PEESG) was extracted with 70% ethanol and purified by HP-20 column chromatography. Its antioxidant and anti-inflammatory activities were evaluated by radical scavenging assay, reducing power determination, and lipopolysaccharide (LPS)-induced RAW264.7 cells assays, respectively. PEESG exhibited obviously scavenging capacity for DPPH and ABTS radicals, as well as significant reducing power for ferric ion. Particularly, PEESG (12.5??50 μg/mL) showed a significantly higher efficiency for scavenging ABTS than that of ascorbic acid and no significant difference with ascorbic acid for DPPH scavenging. PEESG also possessed a significant suppression effect on proinflammatory mediators production, such as nitric oxide (NO), tumor necrosis factor- α± (TNF- α± ), and interleukin-6 (IL-6), in LPS-induced RAW264.7 cells. In addition, the main ingredients of PEESG were identified using ultrahigh pressure liquid chromatography coupled to electrospray mass spectrometry (U-HPLC-ESI-MS). Seventeen components, including 5-O-caffeoylshikimic acid, Neoastilbin, astilbin, neoisoastilbin, isoastilbin, engetin and isoengeletin were identified.

Cas No.

54081-47-9

分子式

C21H22O11

分子量

450.39

别名

新落新妇苷;Neoastilbin

储存和溶解度

DMSO:55 mg/ml (122.12 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years