Vanillylacetone 是一种从生姜中得到的无毒的甲氧基苯酚，具有抗炎、抗糖尿病、抗脂质过敏、抗腹泻、抗痉挛和抗肿瘤等活性。它作为抗有丝分裂剂，能够抑制神经母细胞瘤的生长。它能够缓解氧化应激和炎症，下调 NF-Κb 介导的信号通路。

Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antidiarrhoeic, antilipolytic, antispasmodic and anti-tumor properties. Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways. Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells.

Vanillylacetone is similar in chemical structure to other flavor chemicals such as vanillin and eugenol. It is used as a flavor additive in spice oils and in perfumery to introduce spicy aromas. Fresh ginger does not contain vanillylacetone; cooking the ginger transforms gingerol, which is present, into vanillylacetone through a retro-aldol reaction. Vanillylacetone is likely the active constituent responsible for the antidiarrheal efficacy of ginger. [1]

122-48-5

C11H14O3

194.23

Vanillylacetone;姜酮;Gingerone;NSC 15335

Ethanol:36 mg/mL (185.3 mM)
DMSO:36 mg/mL (185.3 mM)
H2O:10 mg/mL (51.48 mM),warmed
Powder: -20°C for 3 years
In solvent: -80°C for 2 years