6-Shogaol 是从生姜中分离的一种天然产物，具有抗癌、抗炎和抗氧化的多种生物活性。

1. 6-Shogaol has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the femoral cartilage from damage produced in a CFA monoarthritic model of the knee joint of rats. 3. 6-Shogaol inhibits the growth of human cancer cells and induces apoptosis in COLO 25 cells through modulation of mitochondrial functions regulated by reactive oxygen species (ROS). 4. 6-Shogaol effectively inhibit invasion and metastasis of hepatocellular carcinoma through diverse molecular mechanisms, including inhibition of the MAPK and PI3k/Akt pathways and NF-κB and STAT3 activities to suppress expression of MMP-2/-9 and uPA and block angiogenesis, could further regulate urokinase-type plasminogen activity.

555-66-8

C17H24O3

276.37

[6]-Shogaol;姜烯酚;6-Shogaol;6-姜烯酚

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years