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Intoplicine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Intoplicine图片
CAS NO:125974-72-3
包装与价格:
包装价格(元)
5 mg电议
10 mg电议

产品介绍

产品描述

Intoplicine is an inhibitor of DNA topoisomerase I and II.

体外活性

Intoplicine is the most active analogue evaluated in the 7H-benzo[e]-pyrido-[4,3-b]-indole series of antineoplastic compounds. Activity of Intoplicine against human tumor colony-forming units in vitro. Intoplicine shows its activity through inhibition of DNA topoisomerase I and II[1]. Intoplicine is found to unwind DNA and to inhibit purified calf thymus topoisomerase II via stabilization of the ternary cleavable complex[2].

Cas No.

125974-72-3

分子式

C21H24N4O

分子量

348.44

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years