DGAT1-IN-1是DGAT1的高效抑制剂,在Hep3B细胞过表达DGAT1裂解物中,测得IC50低于10nM。
产品描述
DGAT1-IN-1 is a potent inhibitor of diacylglycerol O- acyltransferase type 1(DGAT1, IC50 of< 10 nM).
体外活性
DGAT1 inhibitor Imidazopyridine and imidazothiazole compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme.
Cas No.
1449779-49-0
分子式
C30H28F3N3O4
分子量
551.56
储存和溶解度
DMSO:20 mg/mL (36.26 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years