PI3065 是一种有效的PI3K p110δ抑制剂(IC50=5 nM;Ki=1.5 nM)。它对 p110α，p110β，p110γ 的作用较弱，IC50分别为 910，600，>10000 nM。

PI-3065 is a novel potent and selective PI3K p110δ inhibitor.

PI-3065 shows no inhibition on the growth of 4T1 cells, which do not expressing detectable levels of p110δ. [1]

Proliferation of 4T1 cells is assayed following a 4-h treatment with the indicated p110δ inhibitors, then washing and MTS staining are carried out after 48 h culture. (Only for Reference)

955977-50-1

C27H31FN6OS

506.64

PI3065

DMSO:10.1 mg/mL (20 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years