RAD51-IN-1 是 B02 的衍生物,是一种RAD51的有效抑制剂,可研究癌症。
产品描述
Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.
体外活性
RAD51-IN-1(10μM) decreases the ratio of RAD51 positive cells/cH2AX postive cells in MDA-MB-231 cell exposure to 6 Gy irradiation. RAD51-IN-1 (10μM) significantly inhibits DNA damage induced RAD51 foci formation with 6 Gy irradiation.[1]
Cas No.
2101739-18-6
分子式
C22H16ClN3O
分子量
373.84
储存和溶解度
DMSO:27.5 mg/ml (73.56 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years