SS-208 是一种选择性的 HDAC6 抑制剂 (IC50 = 12 nM)，具有抗肿瘤活性。 SS-208 显示出对其他 HDAC 亚型的选择性。

SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.

In C57BL/6 mice injected immunogenic murine SM1 melanoma cells, SS-208 (25 mg/kg; i.p.) causes a significant reduction of the tumor growth[1].

2245942-72-5

C13H11Cl2N3O4

344.15

DMSO:100 mg/mL (290.6 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years