产品描述
HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM, 1.2 nM, and >500 nM for HDAC1, HDAC6, mTOR and PI3Kα).
体外活性
HDACs/mTOR Inhibitor 1 stimulates cell cycle arrest in the G0/G1 phase and induces tumor cell apoptosis with low toxicity in vivo.
Cas No.
2271413-06-8
分子式
C28H38N8O5
分子量
566.65
储存和溶解度
DMSO:32.5 mg/mL (57.35 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years