BYK204165 是一种选择性PARP1抑制剂，对重组人 PARP1的pIC50值为 7.35，pKi值为7.05。它对鼠 PARP-2的pIC50值为 5.38 ，其对 PARP1 的选择性比对 PARP2 高 100 倍。

BYK204165 is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)

BYK204165 displayed 100-fold selectivity for PARP-1[1].

1104546-89-5

C15H12N2O2

252.273

RT-017290

DMSO:125 mg/mL (495.50 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years