AZ9482 是一种选择性PARP1/2/6的三重抑制剂,IC50值分别为 1 、1 和640 nM。
产品描述
AZ9482 is a selective and potent inhibitor of PARP featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent activity of centrosome declustering with EC50 of< 18 nM in HeLa cells.
Cas No.
1825345-33-2
分子式
C26H22N6O2
分子量
450.49
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years