SIRT1-IN-1 是一种选择性的 SIRT1 抑制剂,IC50 为 205 nM。 SIRT1-IN-1 是一种具有抗病毒活性的巨细胞病毒 (CMV) 抑制剂。
产品描述
SIRT1-IN-1 is a selective inhibitor of SIRT1 with an IC50 of 205 nM. SIRT1-IN-1 is an inhibitor of cytomegalovirus (CMV) with antiviral activity.
体外活性
SIRT1-IN-1 inhibits SIRT2 with an IC50 of 11.5 μM. SIRT1-IN-1 has little effect on SIRT3 (IC50>100 μM) and HDAC (IC50>100 μM)[2].
Cas No.
352554-02-0
分子式
C14H16N2O
分子量
228.29
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years