CP 424174 是一种具有可逆性的IL-1β抑制剂(IC50:210 nM),也能够间接性抑制 NLRP3。
产品描述
CP 424174 is an inhibitor of IL-1β post-translational processing with IC50 of 210 nM. Inhibits the formation of mature IL-1β. Indirectly inhibits NLRP3. Active in vivo and orally bioavailable.
Cas No.
210825-31-3
分子式
C22H29ClN2O4S
分子量
452.99
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years