GSK-3484862 是 有效的DNA 甲基转移酶Dnmt1的非共价抑制剂。GSK-3484862 通过诱导 DNA 低甲基化起抗癌作用。GSK-3484862 介导小鼠胚胎干细胞的整体去甲基化。

Gsk-3484862 is a non covalent inhibitor of DNA methyltransferase DNMT1 with anticancer activity. Gsk-3484862 mediates the global demethylation of mouse embryonic stem cells.

2170136-65-7

C19H19N5OS

365.45

DMSO:20 mg/mL (54.73 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years