AEM1 是Nrf2抑制剂，能够降低 A549 细胞中 Nrf2 依赖基因的表达，并在体外和体内抑制 A549 细胞的生长。

AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer. AEM1 acts by broadly decreasing the expression of NRF2 controlled genes, sensitizing A549 cells to various chemotherapeutic agents, and inhibiting the growth of A549 cells in vitro and in vivo.

1030123-90-0

C20H14FN3O2S

379.41

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years