Prochloraz 是咪唑类抗真菌剂。Prochloraz 抑制羊毛甾醇的细胞色素 P450 依赖性 14α-脱甲基作用，由此抑制麦角固醇的生物合成，从而导致真菌细胞膜破裂和细胞死亡。它也是雌激素受体和 雄激素受体的拮抗剂，IC50分别为25 μM和4 μM， 并激活芳烃受体，EC50为1μM。

Prochloraz is a broad-spectrum contact imidazole fungicide. Prochloraz inhibits human placental microsomal aromatase in vitro (IC50 = 40 nM). Prochloraz also acts as an estrogen receptor (IC50s = 25 μM) and androgen receptor (IC50 = 4 μM) antagonist, and activates aryl hydrocarbon receptors (EC50 = 1 μM).

67747-09-5

C15H16Cl3N3O2

376.67

咪鲜胺;Sporgon;Prelude

DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years