Allopurinol sodium 是黄嘌呤氧化酶抑制剂，其IC50= 0.2~50 μM。它能够抗利什曼原虫，也可用于研究痛风以及高尿酸血症。

EOL-1, human acute myeloid eosinophilic leukemia cell line, was antiproliferative byBI-9564 with EC50 of 800 nM.BRD7 implied as a tumor suppressor and is down-regulated in cancer cells, BI-9564 shows Kd of 73 nM for it, and is >10-fold more selective for BRD9 over the high homologues bromodomain. BI-9564 (<5 μM) shows no activity against 324 kinases, when BI-9564 at 10 μM, an inhibition >40% is observed for only 2 out of 55 GPCRs.

Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.

EOL-1, human acute myeloid eosinophilic leukemia cell line, was antiproliferative byBI-9564 with EC50 of 800 nM.BRD7 implied as a tumor suppressor and is down-regulated in cancer cells, BI-9564 shows Kd of 73 nM for it, and is >10-fold more selective for BRD9 over the high homologues bromodomain. BI-9564 (<5 μm) shows no activity against 324 kinases, when bi-9564 at 10 μm, an inhibition>40% is observed for only 2 out of 55 GPCRs.

17795-21-0

C5H4N4NaO

159.103

1H-吡唑并[3,4-D]嘧啶-4-醇单钠盐;Allopurinol sodium salt;Sodium allopurinol

DMSO:30 mg/mL (188.6 mM)
Ethanol:2 mg/mL (12.57 mM)
H2O:29 mg/mL (182.3 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years