GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment.

GW 766994 (10 μM) reverses CCL11-induced activation of CDK5, phosphorylations of CDK5, GSK3β, and increased phosphorylation of tau in hippocampal neurons.GW 766994 is a specific chemokine receptor-3 (CCR3) antagonist, which has entered clinical trial for asthma and eosinophilic bronchitis.

408303-43-5

C21H24Cl2N4O3

451.35

GW 994

DMSO:56 mg/mL (124.07 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years