SAR407899 hydrochloride 是一种选择性，ATP 竞争性的ROCK抑制剂，对人和大鼠ROCK2的Ki值分别为 36 和 41 nM，对ROCK2的IC50值为 135 nM。

SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively.

923262-96-8

C14H17ClN2O2

280.75

6-(哌啶-4-氧基)异喹啉-1(2H)-酮盐酸盐

H2O:50 mg/mL (178.09 mM),Need ultrasonic
DMSO:25 mg/mL (89.05 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years