NCC007 是一种双酪蛋白激酶 Iα(CKIα)和 δ(CKIδ)抑制剂，IC50分别为 1.8 和 3.6 μM。它通过对longdaysin的N9和C2位进行结构修饰，可研究哺乳动物昼夜节律周期。
产品描述
NCC007 is a novel CKIα and CKIδ dual inhibitors by structural modification of N9 and C2 position of longdaysin.
体外活性
In vitro kinase assay showed that NCC007 inhibited CKIα and CKIδ with an IC50 of 1.8 and 3.6 μM.
体内活性
NCC007 lengthened the period of mouse behavioral rhythms in vivo.
Cas No.
2342583-66-6
分子式
C22H28F3N7
分子量
447.51
储存和溶解度
DMSO:120 mg/mL (268.16mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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