Epiblastin A 是 ATP 竞争性的酪蛋白激酶 1 (CK1) 抑制剂，能够抑制 CK1α (IC50:8.9 μM)、 CK1δ (IC50:0.5 μM)、CK1 ? (IC50:4.7 μM)。它能够抑制 CK1 诱导外胚层干细胞重编程为胚胎干细胞。

Epiblastin A is an inhibitor of Casein Kinase 1 (CK1). Epiblastin A engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs).

16470-02-3

C12H10ClN7

287.71

DMSO:2.5 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years