GS87 是 GSK3（糖原合酶激酶 3）的高度特异性抑制剂，可诱导 AML 细胞的广泛分化。

GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.

GS87 potently inhibits growth of AML cells in mice with little effect on normal bone marrow cells. GS87 causes terminal differentiation of AML cells

919936-70-2

C16H11N5O2S

337.36

4-[5-[[(3-Phenyl-1,2,4-oxadiazol-5-yl)methyl]thio]-1,3,4-oxadiazol-2-yl]pyridine

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years