5-Iodo-indirubin-3'-monoxime 是一种 GSK-3β、CDK5/P25和CDK1/cyclin B抑制剂，IC50值分别为 9、20 和 25 nM，与 ATP 竞争性地结合酶的催化位点。

5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase (IC50s: 9, 20 and 25 nM).

331467-03-9

C16H10IN3O2

403.17

DMSO:66.7 mg/mL (165.43 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years