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MSAB
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MSAB图片
CAS NO:173436-66-3
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
500 mg电议

产品介绍
MSAB 是一种Wnt/β-CATenin信号传导的选择性抑制剂。它能够与 β-CATenin 结合,诱导其降解,并能够下调 Wnt/β-CATenin 靶基因。它对 Wnt 依赖性癌细胞表现出有效的抗肿瘤特性。

产品描述

MSAB is a selective inhibitor of Wnt/β-catenin signaling. MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes.

体内活性

MSAB act against Wnt/β-catenin signaling and identified ?as a selective inhibitor of Wnt/β-catenin signaling.?MSAB shows potent anti-tumor effects selectively on Wnt-dependent cancer cells in vitro and in mouse cancer models.?MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes.?might represent an effective therapeutic strategy for cancers addicted to the Wnt/β-catenin signaling pathway.

Cas No.

173436-66-3

分子式

C15H15NO4S

分子量

305.35

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years