TGFβRI-IN-3 抑制TGFβR1，IC50为 0.79 nM，是对 MAP4K4 的选择性2000 倍。TGFβRI-IN-3 是一种高选择性的 TGFβR1 抑制剂，在免疫肿瘤中具有潜在的应用。

TGFβRI-IN-3 inhibits TGFβR1 with an IC 50 of 0.79 nM with 2000-fold selectivity against MAP4K4. TGFβRI-IN-3 is a highly selective TGFβR1 inhibitor that has potential applications in immuno-oncology [1].

TGFβRI-IN-3 inhibits TGFβR1 at an IC 50 of 0.79 nM, 2000-fold selectivity for MAP4K4 [1].

T9523

C28H23N3O2S

465.57

DMSO:50 mg/mL (107.40 mM),ultrasonic and warming and heat to 60°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years