CUR61414是一种新型的Hedgehog信号通路机制剂，可渗透细胞,可诱导癌细胞凋亡而不影响邻近的非肿瘤细胞。

CUR61414 is a novel, potent and cell permeable Hedgehog signaling pathway inhibitor (IC50 =100-200 nM). CUR61414 is a small-molecule aminoproline class compound and selectively binds to smoothened (Smo) with a Ki value of 44 nM. CUR-61414 can induce apop

T15019L

C31H43ClN4O5

587.15

CUR61414 hydrochloride (334998-36-6 Free base)

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years