Choline chloride 是一种必需营养素，可激活 α7 烟碱受体，具有抗炎、镇痛的活性。对动脉粥样硬化、神经系统疾病和肝脏疾病等具有影响。

Choline chloride is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.

服用Choline chloride后的临床症状表现为烦躁不安,呼吸加速,活动减退,抽搐,皮毛褶皱,走路摇晃和呼吸困难.Choline chloride的急性口服毒性很低.有些动物服用Choline chloride后有腹泻症状.而在一项研究中,尸检时高剂量组中有30%的大鼠肺部发炎.

在细胞培养中,Choline缺乏会导致细胞凋亡或者程序性细胞死亡。

67-48-1

C5H14ClNO

139.63

Hepacholine;Biocoline;Biocolina;氯化胆碱

Ethanol:27 mg/mL (193.4 mM)
DMSO:27 mg/mL (193.4 mM)
H2O:26 mg/mL (186.2 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years