Dopexamine hydrochloride 是β2肾上腺素能受体激动剂。

Dopexamine hydrochloride is a β2-adrenergic receptor agonist. Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow.

Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects. Dopexamine reduces the systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress while not substantially changing systemic hemodynamics, either blood pressure or stroke volume. Dopexamine is a dopamine analogue with agonist activity at β2 and dopaminergic receptors. Dopexamine can attenuate the systemic inflammatory response, reduce tissue leukocyte infiltration, and protect against organ injury at doses that do not alter global hemodynamics or regional microvascular flow.

86484-91-5

C22H34Cl2N2O2

429.42

盐酸多培沙明;FPL60278AR

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years