(R)-Baclofen 是一种选择性GABAB受体激动剂。

(R)-baclofena, a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.

Baclofen is a skeletal muscle relaxant used in the treatment of spasticity of spinal and cerebral origin. Although it is marketed as a racemic mixture, only the baclofen R-enantiomer is stereospecifically active at so called GAGAB-receptors. [1] Researchers believe that the enantiomers of baclofen have different properties. It is claimed that the R-(?)-enantiomer is about 100 times more active than the S-(+)-enantiomer.

69308-37-8

C10H12ClNO2

213.66

Arbaclofen;STX209;(R)-巴氯芬

DMSO:Insoluble
H2O:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years