Spexin acetate(1370290-58-6 free base) 是一种有效的甘丙肽受体 2/3 (GAL2/GAL3) 激动剂（EC50 值分别为 45.7 和 112.2 nM）。对甘丙肽受体 1 没有显着的活性。抑制脂肪细胞对长链脂肪酸的摄取并减少饮食诱导的肥胖小鼠和大鼠的食物消耗。减少金鱼的 LH 分泌。在体内表现出抗焦虑作用。

Spexin acetate is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galanin receptor 1. Endogenous satiety-inducing peptide; inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. Attenuates LH secretion in goldfish. Exhibits anxiolytic effects in vivo.

TP1930L1

C76H117N19O22S

1680.94

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years