Ac-RYYRIK-NH2 acetate 是 nociceptin/orphanin FQ(noc/OFQ) 受体的激动剂，影响自发运动活动。 它是转染在 CHO 细胞中的 ORL1 的部分激动剂，可拮抗大鼠脑膜和切片中 noc/OFQ 对 [35S]-GTPgammaS 与 G 蛋白结合的刺激。

Ac-RYYRIK-NH2 acetate is an agonist at nociceptin/orphanin FQ(noc/OFQ) receptors, affecting spontaneous locomotor activity. Ac-RYYRIK-NH2 acetate is a partial agonist on ORL1 transfected in CHO cells, antagonizes the stimulation of [35S]-GTPgammaS binding to G proteins by noc/OFQ in membranes and sections of rat brain.

When administered intracerebroventricularly (i.c.v.), Ac-RYYRIK-NH inhibited spontaneous locomotor activity in mice with ID50 of 0.07 nmol, respectively[1].

TP1940L1

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years