Norbinaltorphimine dihydrochloride is a potent and selective antagonist of κ opioid receptor.

The KOR antagonist, Norbinaltorphimine(norBNI), had weak and inconsistent effects on THC-induced taste avoidance in adolescent rats in that norBNI both attenuated and strengthened taste avoidance dependent on dose and trial.?norBNI had limited impact on the final one-bottle avoidance and no effects on the two-bottle preference test.?Interestingly, norBNI had no effect on THC-induced taste avoidance in adult rats as well.

113158-34-2

C40H45Cl2N3O6

734.72

nor-BNI dihydrochloride;nor-Binaltorphimine dihydrochloride

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years