Hoechst 34580 xHCl(23555-00-2(free base) 是一种可渗透细胞的荧光染料，用于染色 DNA 和细胞核。

Hoechst 34580 xHCl is a cell-permeable fluorescent dye, is used for staining DNA and nuclei.

Hoechst 34580 is a good candidate for treating Alzheimer’s disease by inhibiting Aβ formation. 50 μM Aβ42 solutions co-incubated with 100, 25, 12.5, 3.125, 0.78, and 0.1, 0.01 μM Hoechst 34580 at 37 °C for 70 h. Hoechst 34580 can inhibit the aggregation of Aβ42 in a dose-dependent manner. The IC50 is obtained by measuring the concentration of Hoechst 34580 while maintaining the Aβ42 concentration which gave 0.86±0.05 μM for Hoechst 34580.

T19011L

C27H29N7.xHCl

HOE 34580 xHCl

DMSO:11 mg/ml,Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years