AG 555是一种选择性EGFR的有效抑制剂，可阻断CDK2活化。它是一种抗逆转录病毒药。

AG 555 is an EGFR tyrosine kinase inhibitor.

Cell incubation in the presence of 30 μM AG 555 results in a selective down-regulation of the most abundant viral transcripts already 4 h after drug application. AG55 inhibits the growth of HPV16-immortalized cells. AG555 is already effective at 10 μM (IC50=6.4, respectively), and the cells remain arrested after withdrawal of the compound on day 5 as monitored on days 8 and 12.

133550-34-2

C19H18N2O3

322.364

Tyrphostin AG 555;Tyrphostin B46

DMSO:9.7 mg/mL(30 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years