EGFR-IN-9 是一种有效的 EGFR 激酶抑制剂，对于野生型 EGFR 激酶和双重突变型 EGFR 激酶 (L858R/T790M) 的 IC50 分别为 7 nM 和 28 nM。EGFR-IN-9 具有抗肿瘤活性。

EGFR-IN-9 is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity.

EGFR-IN-9 shows antiproliferative activity in HCC827 lung cancer cell line with an IC50 of 8 nM[1].

1226549-39-8

C29H24N4O3

476.53

DMSO:90mg/mL (188.9mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years