SYR127063 是一种有效的选择性 HER2 抑制剂，以反应构象与 HER2 结合。

SYR127063 (BDBM92454) is a potent and selective HER2 inhibitor, binds to HER2 in a reactive conformation.

IC50 data: HER2 = 11 nM; EGFR = 429 nM; HER4 >10000 nM

871026-18-5

C23H20ClF3N4O3

492.88

BDBM 92454;BDBM92454;SYR-127063;SYR 127063;BDBM-92454

DMSO:Soluble
H2O:Insoluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years