Adaphostin 是 AG957 金刚烷酯，是一种 p210bcr/abl抑制剂，可诱导 T 淋巴细胞白血病细胞系凋亡。它增加了 CLL B 细胞内活性氧的水平，对慢性和急性髓系白血病细胞具有显著的选择性活性。

Adaphostin is a p210Bcr/Abl tyrosine kinase inhibitor with IC50 of 14 μM.

It also induces apoptosis in T-lymphoblastic human leukemia cell lines (IC50 values range from 16.8 to 216.3 nM) in vitro.

Adaphostin can damage both myeloid and lymphoid leukemia cells[2].

241127-58-2

C24H27NO4

393.48

1-Adamantyl 4-((2,5-Dihydroxybenzyl)Amino)Benzoate;NSC 680410

Ethanol:<40 mgml (101.66 mm)
DMSO:<40 mgml (101.66 mm)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years