GNE-9815 是一种高激酶选择性 Raf 抑制剂,可用于通过联合治疗靶向 KRas 突变癌症。
产品描述
GNE-9815 is a high kinase-selective inhibitor of RAF and targets KRAS-mutant cancers through combination therapy.
Cas No.
2729996-45-4
分子式
C26H22FN5O2
分子量
455.48
别名
3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide
储存和溶解度
DMSO:45 mg/mL (98.80 mM),ultrasonic and warming and heat to 80°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years