Seralutinib 是可吸入的PDGFRα 和 PDGFRβ激酶抑制剂，可用于研究肺动脉高压。

Seralutinib is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension.

GB002 dose- and time-dependently induces lung BMPR2 protein expression.GB002-mediated inhibition of lung PDGFRα/β phosphorylation in healthy Sprague Dawley rats immediately post inhalation[1].

1619931-27-9

C27H27N5O3

469.545

GB002

DMSO:100 mg/mL (212.98 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years